Evidence-based medicine started out with Archie Cochrane in 1972 and really hit big time with David Sackett, David Eddy and others in the ...

This is going to be short and sweet. Pharmalot reported two days ago that abandonment rate for all new prescriptions for brand-name drugs...

This post was in part inspired by my recent exchange with e-Patient Dave . But really I have been thinking about this for quite some time no...

T his is a post I did originally for BMJ's doc2doc site . I am cross-posting it here for your convenience. Lately I find myself getting...

Dr. Novella continues with his egregious oversimplification of the concept of science-based medicine here . I again felt compelled to respon...

One of the top hits that comes up on the Oracle of Googlius for "astroturf" is for the original company, now renamed SYNLawn , but...

OK, so when I was in practice I pretty much worked every day, including weekends, even when not on call, and can attest to the burn-out pote...

I have been working on a talk for the American College of Chest Physicians (Chest) annual meeting. The session is on alternative research st...

A good friend of mine lost her mother to pancreatic cancer recently. The whole process from diagnosis to her death took 6 weeks. And despite...

My students and I are continuing with the VAP theme, this week exploring the development and implementation of evidence-based practice guide...

This week in my class we are talking about systematic reviews and meta-analyses. As in the past, I assigned this excellent example published...

"When men are most sure and arrogant they are commonly most mistaken, giving views to passion without that proper deliberation which al...